Search results for "Infectious Diseases"
Common outpatient meds, interferon beta show positive results for COVID-19
A retrospective study found lower mortality rates in COVID-19 patients who were taking drugs including statins, metformin, and angiotensin-converting enzyme inhibitors, while a trial found faster recovery in patients who received interferon beta in addition to remdesivir.
https://acphospitalist.acponline.org/archives/2022/07/06/free/common-outpatient-meds-interferon-beta-show-positive-results-for-covid-19.htm
6 Jul 2022
Six-month home MRSA decolonization protocol after hospital discharge appears effective
A secondary analysis of a multicenter randomized clinical trial found reduced colonization with methicillin-resistant Staphylococcus aureus (MRSA) overall and at multiple body sites in those assigned to decolonize with chlorhexidine and mupirocin.
https://acphospitalist.acponline.org/archives/2022/06/08/six-month-home-mrsa-decolonization-protocol-after-hospital-discharge-appears-effective.htm
8 Jun 2022
Treatment combos, ECMO outcomes, vaccine protection in COVID-19
Recent studies compared baricitinib with dexamethasone in COVID-19 patients requiring oxygen, assessed outcomes of extracorporeal membrane oxygenation (ECMO) over time, and found that the vaccines continue to reduce risk for ICU admission and death despite new variants' emergence.
https://acphospitalist.acponline.org/archives/2022/06/01/free/treatment-comparisons-ecmo-outcomes-vaccination-effects-in-covid-19.htm
1 Jun 2022
Aerosols flowed from one bed to another in shared hospital rooms
Closing the curtains between hospital beds was actually more effective in reducing aerosol transfer than using a portable air cleaner, according to a recent simulation study of a double-occupancy room.
https://acphospitalist.acponline.org/archives/2022/05/04/free/aerosols-flowed-from-one-bed-to-another-in-shared-hospital-rooms.htm
4 May 2022
OPAT has similar safety, lower costs versus inpatient antibiotic therapy
Patients receiving outpatient parenteral antimicrobial therapy (OPAT) after hospitalization for bacterial infection had 90-day adverse event rates of 35.6% compared to 39.0% in those who stayed in the hospital for parenteral antimicrobial therapy, a retrospective Canadian study found.
https://acphospitalist.acponline.org/archives/2022/04/27/opat-has-similar-safety-lower-costs-versus-inpatient-antibiotic-therapy.htm
27 Apr 2022
Gram stain-guided antibiotics for VAP noninferior to guideline-based therapy
Compared with guideline-based treatment, treatment guided by Gram staining significantly reduced use of broad-spectrum antibiotics and yielded similar clinical responses in patients with ventilator-associated pneumonia (VAP), a Japanese trial found.
https://acphospitalist.acponline.org/archives/2022/04/13/gram-stain-guided-antibiotics-for-vap-noninferior-to-guideline-based-therapy.htm
13 Apr 2022
Rapid testing of health care workers with COVID-19 found many still positive at day 5
Rapid antigen testing for SARS-CoV-2 could be a safe and effective method for guiding return to work, according to the authors of a retrospective study of health care personnel infected in January.
https://acphospitalist.acponline.org/archives/2022/04/06/free/rapid-testing-of-health-care-workers-with-covid-19-found-many-still-positive-at-day-5.htm
6 Apr 2022
Fecal microbiota transplant appears cost-effective for first recurrent C. diff infection
A modeling study found the greatest cost-effectiveness with fidaxomicin for initial nonsevere Clostridioides difficile infection, with vancomycin for initial severe infection, and with fecal microbiota transplant for first and subsequent recurrent infection.
https://acphospitalist.acponline.org/archives/2022/03/23/fecal-microbiota-transplant-appears-cost-effective-for-first-recurrent-c-diff-infection.htm
23 Mar 2022
Real-time clinical decision support associated with improved pneumonia care
A trial at 16 hospitals in Utah found lower mortality rates, improved antibiotic prescribing, and increased discharge to home after deployment of guideline-based electronic clinical decision support for pneumonia care in the ED.
https://acphospitalist.acponline.org/archives/2022/03/16/real-time-clinical-decision-support-associated-with-improved-pneumonia-care.htm
16 Mar 2022
Benefits of dedicated COVID-19 hospitals, ECMO; air sampling after aerosol-generating procedures
A health system reported outcomes at two hospitals created to treat only COVID-19. Another found that 42.9% of COVID-19 patients who got ECMO died, compared to 89.1% when it wasn't available. A sampling study compared viral particles in the air with different procedures.
https://acphospitalist.acponline.org/archives/2022/03/09/free/benefits-of-dedicated-covid-19-hospitals-ECMO-air-sampling-after-aerosol-generating-procedures.htm
9 Mar 2022