Search results for "Infectious Diseases"
Patients with discordant C. difficile test results had lower mortality with treatment
Patients who were positive for Clostridioides difficile on nucleic acid amplification testing but negative on toxin immunoassay had similar 30-day mortality to those with positive results on both tests, according to a review of observational studies.
https://acphospitalist.acponline.org/archives/2023/09/13/patients-with-discordant-c-difficile-test-results-had-lower-mortality-with-treatment.htm
13 Sep 2023
Guidelines on resistant gram-negatives
Hospitalists are some of the best antibiotic stewards, according to the lead author of recent guidance that aims to help them manage tricky infections.
https://acphospitalist.acponline.org/archives/2023/09/06/free/guidelines-on-resistant-gram-negatives.htm
6 Sep 2023
Infectious diseases, hospital organizations update strategies for CAUTI prevention
The recommendations include essential practices for preventing catheter-associated urinary tract infections (CAUTIs), which apply to all acute care hospitals, and additional approaches, which should be considered when essential practices have been implemented but infection rates remain high.
https://acphospitalist.acponline.org/archives/2023/08/30/infectious-diseases-hospital-organizations-update-strategies-for-cauti-prevention.htm
30 Aug 2023
First-line antibiotic options for CAP on the wards show similar mortality rates
A large retrospective study of patients with community-acquired pneumonia (CAP) found similar inpatient mortality with a beta-lactam plus a macrolide, a beta-lactam plus doxycycline, or a respiratory fluoroquinolone. A beta-lactam alone appeared less effective.
https://acphospitalist.acponline.org/archives/2023/08/23/first-line-antibiotic-options-for-cap-on-the-wards-show-similar-mortality-rates.htm
23 Aug 2023
Catching C. diff cases, not colonization
Researchers have found innovative ways to improve hospital systems for diagnosing Clostridioides difficile.
https://acphospitalist.acponline.org/archives/2023/08/16/catching-c-diff-cases-not-colonization.htm
16 Aug 2023
Hospital antibiograms may not be accurate for selecting initial empiric therapy
A retrospective cohort study of Veterans Health Administration facilities found that facility-level antibiograms had limited utility in predicting individual resistance for Escherichia coli and Klebsiella species in individual patients.
https://acphospitalist.acponline.org/archives/2023/08/16/hospital-antibiograms-may-not-be-accurate-for-selecting-initial-empiric-therapy.htm
16 Aug 2023
Time to antibiotics matters for septic shock, not so much for sepsis without shock
Every hour that antibiotics were delayed was associated with higher mortality from septic shock, but patients with sepsis and no shock only had elevated risk of death if their antibiotics were not administered within six hours, according to a new analysis.
https://acphospitalist.acponline.org/archives/2023/08/09/time-to-antibiotics-matters-for-septic-shock-not-so-much-for-sepsis-without-shock.htm
9 Aug 2023
IDSA updates guidance on managing drug-resistant, gram-negative infections
New treatment recommendations from the Infectious Diseases Society of America (IDSA) dealt with resistant strains of Enterobacterales, Pseudomonas aeruginosa, Acinetobacter baumannii, and Stenotrophomonas maltophilia.
https://acphospitalist.acponline.org/archives/2023/07/26/idsa-updates-guidance-on-managing-drug-resistant-gram-negative-infections.htm
26 Jul 2023
Relaxing MRSA precautions during pandemic associated with higher infection rate
Veterans Affairs hospitals that abandoned active surveillance and contact precautions for methicillin-resistant Staphylococcus aureus (MRSA) had significantly higher rates of hospital-acquired MRSA than those that continued the measures.
https://acphospitalist.acponline.org/archives/2023/07/12/relaxing-mrsa-precautions-during-pandemic-associated-with-higher-infection-rate.htm
12 Jul 2023
Procalcitonin do's and don'ts
Although the optimal use of procalcitonin is still up for debate, there are best practices for getting the most bang for this blood test.
https://acphospitalist.acponline.org/archives/2023/07/05/free/procalcitonin-dos-and-donts.htm
5 Jul 2023